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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1272
PMID24371517
Year2013
BiomarkerIntegrin α3 [ITGA3]
Biomarker BasisExpression Based
BiomoleculeProtein
SourceUrine
SubjectsHumans
RegulationUpregulated in Metastatic Prostate Cancer
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways include: Dilated cardiomyopathy, Hematopoietic cell lineage, Cell surface interactions at the vascular wall, Integrin-mediated cell adhesion, Integrin cell surface interactions
ExperimentMetastasis Vs Prostate Cancer and BPH
Type of BiomarkerDiagnostic
CohortPatients with Benign Prostatic Hyperplasia BPH (n=5), Prostate Cancer PCa (n=5) and metastatic PCa (n=3) were selected for evaluation of protein expression in the exosomes
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.005
Method UsedWestern Blotting
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on Human Patient Cohort
Technical NameITGA3