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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1271
PMID24371517
Year2013
BiomarkerITGA3; ITGB1; TLN1; VCL; ITGA1; FLNC;
Biomarker BasisExpression Based
BiomoleculeProtein
SourceCell Lines
SubjectsHumans
RegulationDifferentially Expressed
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on Pathwayscell adhesion, cell-matrix adhesion and integrin-mediated signalling pathway
ExperimentLNCaP Cell Lines Vs PC-3 Cell Lines
Type of BiomarkerPrognostic
CohortExosomes from LNCaP and PC-3 cancer cell lines were chosen for analysis
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.05
Method UsedLiquid chromatography–mass spectrometry
ClinicalNo
RemarksPC3 is hormone-independently growing, more aggressive and LNCaP is hormone depen- dently, less aggressive
Clinical Trial NumberNA
Degree Of ValidityValidated on Human Patient Cohort
Technical NameITGA3, ITGB1, TLN1, VCL, ITGA1, FLNC