Biomarker ID | 1271 |
PMID | 24371517 |
Year | 2013 |
Biomarker | ITGA3; ITGB1; TLN1; VCL; ITGA1; FLNC; |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Cell Lines |
Subjects | Humans |
Regulation | Differentially Expressed |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | cell adhesion, cell-matrix adhesion and integrin-mediated signalling pathway |
Experiment | LNCaP Cell Lines Vs PC-3 Cell Lines |
Type of Biomarker | Prognostic |
Cohort | Exosomes from LNCaP and PC-3 cancer cell lines were chosen for analysis |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | Liquid chromatography–mass spectrometry |
Clinical | No |
Remarks | PC3 is hormone-independently growing, more aggressive and LNCaP is hormone depen- dently, less aggressive |
Clinical Trial Number | NA |
Degree Of Validity | Validated on Human Patient Cohort |
Technical Name | ITGA3, ITGB1, TLN1, VCL, ITGA1, FLNC |