| Biomarker ID | 127 |
| PMID | 16614113 |
| Year | 2006 |
| Biomarker | Neuropeptide Y (NPY) |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Increased expression with increase in relapse |
| Odds Ratio/Hazard Ratio/Relative Risk | Univariate: HR: 1.3 (95% CI: 1.1-1.6); Multivariate: 1.5 (955 CI: 1.2-1.8) |
| Effect on Pathways | Pathways Include:-Adipocytokine signaling pathway, Peptide G-protein coupled receptors,G alpha (i) signaling events, GPCR ligand binding,Signaling by GPCR |
| Experiment | Relapse Vs No Relapse after Radical Prosteactomy |
| Type of Biomarker | Prognostic |
| Cohort | 245 patients who underwent radical prostatectomy having benign, low-grade prostatic intraepithelial neoplasia (PIN), high-grade PIN (HGPIN), and prostate cancer tissue werw taken into examination |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.037 |
| Method Used | Immunohistochemistry |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NPY |