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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1263
PMID24358122
Year2013
Biomarkerβ-catenin
Biomarker BasisExpression Based
BiomoleculemRNA
SourceCell Lines
SubjectsHumans
RegulationDownregulated in: [CAHPV-10 (3 fold)] ;Upregulated in [LNCaP: (3.8 fold) DU145 (2.2 fold); PC-3 (2.1 fold)]
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysNA
ExperimentCAHPV-10, DU145, PC-3, LNCaP Vs PNT2
Type of BiomarkerDiagnostic
CohortCell lines derived from normal prostate epithelial tissue (PNT2), non-invasive (CAHPV-10) and invasive prostate cancer (LNCaP, DU145, PC-3) were taken for this study
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of SignificanceCAHPV-10 (p= 0.015); DU145 (p=0.001); PC-3 (p=0.001) LNCap: (p<0.001)
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on human patient cohort
Technical NameNA