Biomarker ID | 1259 |
PMID | 24358122 |
Year | 2013 |
Biomarker | Claudin 7 |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Cell Lines |
Subjects | Humans |
Regulation | Downregulated in: [DU145 (5.3 fold); PC-3 (24.8 fold)];Upregulated in LNCaP: (4.63 fold) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | CAHPV-10, DU145, PC-3, LNCaP Vs PNT2 |
Type of Biomarker | Diagnostic |
Cohort | Cell lines derived from normal prostate epithelial tissue (PNT2), non-invasive (CAHPV-10) and invasive prostate cancer (LNCaP, DU145, PC-3) were taken for this study |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | DU145 (p=0.004); PC-3 (p= 0.01); LNCaP (p = 0.001) |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on human patient cohort |
Technical Name | NA |