Biomarker ID | 1254 |
PMID | 24292680 |
Year | 2013 |
Biomarker | Forkhead Box A1 [FOXA1] |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Increased in shorter time to Biochemical Recurrence |
Odds Ratio/Hazard Ratio/Relative Risk | HR: 5.0 (95% CI: 1.2–21.1) |
Effect on Pathways | Pathways include: HNF3A pathway, HNF3B pathway, p53 signaling pathway |
Experiment | Biochemical recurrence Vs No Biochemical Recurrence |
Type of Biomarker | Prognostic |
Cohort | 102 prostate cancer patients were chosen for the study, out of which 26 had low FOXA1 H score and 76 had high FOXA1 H score |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p = 0.028 |
Method Used | Tissue Microarray |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |