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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1254
PMID24292680
Year2013
BiomarkerForkhead Box A1 [FOXA1]
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationIncreased in shorter time to Biochemical Recurrence
Odds Ratio/Hazard Ratio/Relative RiskHR: 5.0 (95% CI: 1.2–21.1)
Effect on PathwaysPathways include: HNF3A pathway, HNF3B pathway, p53 signaling pathway
ExperimentBiochemical recurrence Vs No Biochemical Recurrence
Type of BiomarkerPrognostic
Cohort102 prostate cancer patients were chosen for the study, out of which 26 had low FOXA1 H score and 76 had high FOXA1 H score
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep = 0.028
Method UsedTissue Microarray
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA