Biomarker ID | 1251 |
PMID | 24266816 |
Year | 2013 |
Biomarker | Active Hepatocyte Growth Factor [aHGF] |
Biomarker Basis | Concentration Based (pg/mL) |
Biomolecule | Protein |
Source | Urine |
Subjects | Humans |
Regulation | Upregulated in PCa: [Controls: 111.3; Localised PCa: 235.2] |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Prostate Cancer Vs No Prostate Cancer |
Type of Biomarker | Diagnostic |
Cohort | Healthy men (n = 19) and men with localized (n = 65) and metastatic (n = 36) Prostate Cancer were chosen as the cohort |
Senstivity | 85% |
Specificity | 32% |
AUC | 0.76 (95% CI: 0.65–0.87) |
Accuracy | NA |
Level Of Significance | p = 0.003 |
Method Used | ELISA |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |