Biomarker ID | 1249 |
PMID | 24255071 |
Year | 2013 |
Biomarker | Lactate Dehydrogenase [LDH] |
Biomarker Basis | Concentration Based (U/L) |
Biomolecule | Protein |
Source | Blood |
Subjects | Humans |
Regulation | NA |
Odds Ratio/Hazard Ratio/Relative Risk | Univariate Analysis: HR: [2.68 (95% CI: 1.72–4.18)] Multivariate Analysis: [1.75 (95% CI: 1.08–2.82)] |
Effect on Pathways | Pathways include: TRXA, RPLF, CLPP, PRS, RPOB |
Experiment | Overall Survival Vs No Survival |
Type of Biomarker | Prognostic |
Cohort | 201 patients with Prostate cancer were defined as the cohort. They were randomised into 134 tasquinimod and 67 placebo arms. |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | Univariate: p < 0.001; Multivariate: p =0.023 |
Method Used | Assays |
Clinical | Yes |
Remarks | NA |
Clinical Trial Number | NCT00560482 |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |