| Biomarker ID | 1248 |
| PMID | 24255071 |
| Year | 2013 |
| Biomarker | Thrombospondin-1 [TSP-1] |
| Biomarker Basis | Concentration Based (μg/L) |
| Biomolecule | Protein |
| Source | Plasma |
| Subjects | Humans |
| Regulation | Increased levels indicate better overall survival in Tasquinimod arm |
| Odds Ratio/Hazard Ratio/Relative Risk | HR: 0.54 |
| Effect on Pathways | NA |
| Experiment | Overall Survival in Tasquinimod Vs Overall Survival in Placebo arm |
| Type of Biomarker | Predictive |
| Cohort | 201 patients with Prostate cancer were defined as the cohort. They were randomised into 134 tasquinimod and 67 placebo arms. |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p=0.034 |
| Method Used | ELISA |
| Clinical | Yes |
| Remarks | (n= 95) TSP1 ≤ 1370 μg/L and (n=94) TSP1 >1370 μg/L were chosen as the classification Criteria |
| Clinical Trial Number | NCT00560482 |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |