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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1245
PMID24240687
Year2013
Biomarker N-acetyl-L-aspartyl-L-glutamate peptidase-like 2 (NAALADL2 )
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsHumans
RegulationUpregulated with High Gleason Score
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways include: SGK494 human kinase ARCHS4 coexpression, SCYL3 human kinase ARCHS4 coexpression, AURKC human kinase ARCHS4 coexpression, BMPR1B human kinase ARCHS4 coexpression, RPS6KA5 human kinase ARCHS4 coexpression
ExperimentGleason Score 3 Vs 4 Vs 5
Type of BiomarkerPrognostic
Cohort222 Benign Tissues along with 511 Prostate Cancer tissues were chosen for evaluation. Out of 511 cancerous tissue, 324 had Gleason Score (GS) 3, 168 had GS 4, 19 had GS 5
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep=0.028
Method UsedImmunohistochemistry
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameNAALADL2