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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1240
PMID24211598
Year2014
BiomarkerProstate cancer antigen 3 [PCA3]
Biomarker BasisExpression Based
BiomoleculemRNA
SourceUrine
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways include: Proteins Involved in Prostate Cancer
ExperimentProstate Cancer Vs No Prostate Cancer
Type of BiomarkerDiagnostic
CohortA total of 30 patients were included in study, from whom a total of 60 urinary samples were collected. For analysis we used a urinary sample obtained before and after DRE from each patient.
SenstivityNA
SpecificityNA
AUC0.808 (95% CI 0.64- 0.98)
AccuracyNA
Level Of SignificanceNA
Method UsedRT-PCR
ClinicalNo
RemarksAUC Values for PCA3 Cell Pellet - After Digital Rectal Exam (DRE)
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NamePCA3