Biomarker ID | 1240 |
PMID | 24211598 |
Year | 2014 |
Biomarker | Prostate cancer antigen 3 [PCA3] |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Urine |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: Proteins Involved in Prostate Cancer |
Experiment | Prostate Cancer Vs No Prostate Cancer |
Type of Biomarker | Diagnostic |
Cohort | A total of 30 patients were included in study, from whom a total of 60 urinary samples were collected. For analysis we used a urinary sample obtained before and after DRE from each patient. |
Senstivity | NA |
Specificity | NA |
AUC | 0.808 (95% CI 0.64- 0.98) |
Accuracy | NA |
Level Of Significance | NA |
Method Used | RT-PCR |
Clinical | No |
Remarks | AUC Values for PCA3 Cell Pellet - After Digital Rectal Exam (DRE) |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | PCA3 |