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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1235
PMID24183365
Year2014
BiomarkerProstate Stem Cell Antigen (PSCA)
Biomarker BasisExpression Based
BiomoleculeProtein
SourceTissue
SubjectsHumans
RegulationUpregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways inlcude: MAPK15 human kinase ARCHS4 coexpression, MAP3K19 human kinase ARCHS4 coexpression, RIPK4 human kinase ARCHS4 coexpression, ERN2 human kinase ARCHS4 coexpression
ExperimentGleason Score 6 Vs Gleason Score 8
Type of BiomarkerDiagnostic
Cohort114 prostate cancers (PCa), 21 High Grade Pros- tatic Intraepithelial Neoplasias (HGPIN) and 50 samples of benign prostate tissue - All from Iranian origin were taken for the study. 45 with Gleason Score 6, 50 with Gleason Score 7 and 5 with Gleason Score 8
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep<0.05
Method UsedImmunohistochemistry
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA