Biomarker ID | 1235 |
PMID | 24183365 |
Year | 2014 |
Biomarker | Prostate Stem Cell Antigen (PSCA) |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways inlcude: MAPK15 human kinase ARCHS4 coexpression, MAP3K19 human kinase ARCHS4 coexpression, RIPK4 human kinase ARCHS4 coexpression, ERN2 human kinase ARCHS4 coexpression |
Experiment | Gleason Score 6 Vs Gleason Score 8 |
Type of Biomarker | Diagnostic |
Cohort | 114 prostate cancers (PCa), 21 High Grade Pros- tatic Intraepithelial Neoplasias (HGPIN) and 50 samples of benign prostate tissue - All from Iranian origin were taken for the study. 45 with Gleason Score 6, 50 with Gleason Score 7 and 5 with Gleason Score 8 |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | Immunohistochemistry |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |