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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1228
PMID24167554
Year2013
BiomarkermiR-99b
Biomarker BasisExpression Based
BiomoleculemiRNA
SourceTissue
SubjectsHumans
RegulationDownregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:- metabolic process; Somatroph axis (GH) and its relationship to dietary restriction and aging; cellular metabolic process; macromolecule metabolic process; intracellular membrane-bounded organelle
ExperimentProstate Cancer Vs Adjacent Normal
Type of BiomarkerDiagnostic
Cohort40 PCa patients with Gleason (GS) 6–7 and adjacent normal regions were profiled (including the 10 in discovery set)
SenstivityNA
SpecificityNA
AUC0.86 (95% CI: 0.78– 0.95)
AccuracyNA
Level Of Significancep<0.0001
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NamemiR-99b