Biomarker ID | 1225 |
PMID | 24167554 |
Year | 2013 |
Biomarker | miR-205 |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Downregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; positive regulation of cellular metabolic process; positive regulation of metabolic process; nervous system development |
Experiment | Prostate Cancer Vs Adjacent Normal |
Type of Biomarker | Diagnostic |
Cohort | 40 PCa patients with Gleason (GS) 6–7 and adjacent normal regions were profiled (including the 10 in discovery set) |
Senstivity | NA |
Specificity | NA |
AUC | 0.83 (95% CI: 0.74–0.91) |
Accuracy | NA |
Level Of Significance | p<0.0001 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | miR-205 |