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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1225
PMID24167554
Year2013
BiomarkermiR-205
Biomarker BasisExpression Based
BiomoleculemiRNA
SourceTissue
SubjectsHumans
RegulationDownregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; positive regulation of cellular metabolic process; positive regulation of metabolic process; nervous system development
ExperimentProstate Cancer Vs Adjacent Normal
Type of BiomarkerDiagnostic
Cohort40 PCa patients with Gleason (GS) 6–7 and adjacent normal regions were profiled (including the 10 in discovery set)
SenstivityNA
SpecificityNA
AUC0.83 (95% CI: 0.74–0.91)
AccuracyNA
Level Of Significancep<0.0001
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NamemiR-205