Biomarker ID | 1221 |
PMID | 24115268 |
Year | 2014 |
Biomarker | β-Microseminoprotein |
Biomarker Basis | Expression Based |
Biomolecule | Protein |
Source | Urine |
Subjects | Humans |
Regulation | Downregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Prostate Cancer Vs Other Prostatic Conditions |
Type of Biomarker | Diagnostic |
Cohort | 25 participants with prostate cancer (PCa) and 27 participants with a variety of benign prostatic conditions [BPH( n=11), Prostatitis (n=20), Atrophy (n=12)]were included in the study. [Non cancer prostatis conditions were overlapping for patients] |
Senstivity | NA |
Specificity | NA |
AUC | 0.6978 |
Accuracy | NA |
Level Of Significance | p = 0.01 |
Method Used | MALDI- MS |
Clinical | No |
Remarks | A peak at m/z 10,760 was identified as b-microseminoprotein (b-MSMB) |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | MSMB |