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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1221
PMID24115268
Year2014
Biomarkerβ-Microseminoprotein
Biomarker BasisExpression Based
BiomoleculeProtein
SourceUrine
SubjectsHumans
RegulationDownregulated in PCa
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysNA
ExperimentProstate Cancer Vs Other Prostatic Conditions
Type of BiomarkerDiagnostic
Cohort25 participants with prostate cancer (PCa) and 27 participants with a variety of benign prostatic conditions [BPH( n=11), Prostatitis (n=20), Atrophy (n=12)]were included in the study. [Non cancer prostatis conditions were overlapping for patients]
SenstivityNA
SpecificityNA
AUC0.6978
AccuracyNA
Level Of Significancep = 0.01
Method UsedMALDI- MS
ClinicalNo
RemarksA peak at m/z 10,760 was identified as b-microseminoprotein (b-MSMB)
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameMSMB