Biomarker ID | 1220 |
PMID | 24097862 |
Year | 2013 |
Biomarker | Semaphorin 4F (SF4) |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated (high levels) had increased risk of biochemical recurrence |
Odds Ratio/Hazard Ratio/Relative Risk | HR: 5.43; (95% CI: 2.19–13.40) |
Effect on Pathways | NA |
Experiment | Biochemical recurrence Vs No Biochemical Recurrence |
Type of Biomarker | Prognostic |
Cohort | 240 patients were chosen for the study out of which 28 had biochemical recurrence |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p = 0.0002 |
Method Used | RT-PCR |
Clinical | No |
Remarks | high expression group (S4F ≥ 4.35; 13 cases) or low expression group (S4F < 4.35; 227 cases) |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | SF4 |