Biomarker ID | 1217 |
PMID | 24081904 |
Year | 2014 |
Biomarker | Cytochrome P450 family 24 subfamily A member 1 (CYP24A1) |
Biomarker Basis | Concentration Based |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: Vitamin D biosynthesis, Vitamin D (calciferol) metabolism, Cytochrome P450 metabolism of vitamins, Steroid hormone, vitamin A, and vitamin D metabolism, Nuclear receptors in lipid metabolism and toxicity |
Experiment | Prostate Cancer Vs Benign Prostatic Hyperplasia |
Type of Biomarker | Diagnostic |
Cohort | 8 malignant and paired adjacent normal tissues were used for analysis |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p = 0.03 |
Method Used | Immunohistochemistry |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | CYP24A1 |