Biomarker ID | 1214 |
PMID | 24080222 |
Year | 2013 |
Biomarker | PCA3 |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Urine |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: Proteins Involved in Prostate Cancer |
Experiment | Prostate Cancer Vs Normal Prostate |
Type of Biomarker | Diagnostic |
Cohort | 71 consecutive patients with clinically suspected PCa were included in the study. 68 had PCa and 95 did not. |
Senstivity | 0.68 (95% CI: 0.57-0.79) |
Specificity | 0.66 (95% CI: 0.57-0.76) |
AUC | 0.67 (95% CI: 0.60-0.74) |
Accuracy | 0.67 (95% CI: 0.60-0.74) |
Level Of Significance | NA |
Method Used | NA |
Clinical | No |
Remarks | Results (Accuracy, Sensitivity, Specificity, AUC) shown for PCA3 ≥ 44 |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |