Biomarker ID | 1206 |
PMID | 23991666 |
Year | 2013 |
Biomarker | Neuropeptideâ€Y (NPY) |
Biomarker Basis | Concentration Based |
Biomolecule | Protein |
Source | Plasma |
Subjects | Humans |
Regulation | Upregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: Adipocytokine signaling pathway, Peptide G-protein coupled receptors, G alpha (i) signaling events, GPCR ligand binding, Signaling by GPCR |
Experiment | Prostate Cancer Vs (Normal and BPH patients) |
Type of Biomarker | Diagnostic |
Cohort | Plasma from 24 healthy controls, 19 benign prostate hypertrophy patients, and 73 prostate cancer patients was taken |
Senstivity | 41.5% |
Specificity | 97.8% |
AUC | 0.717 |
Accuracy | NA |
Level Of Significance | p = 0.0396 |
Method Used | QUEST-MS (Quick Enrichment of Small Targets for Mass Spectrometry) |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |