Biomarker ID | 1199 |
PMID | 23935962 |
Year | 2013 |
Biomarker | miR-210 |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in PCa [Cohort 1: 6.9 fold; Cohort 2: 3.1 fold] |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:- nervous system development; neuron differentiation;synapse; anatomical structure morphogenesis; neuron development |
Experiment | Controls Vs Metastatic Castration Resistant Prostate Cancer (mCRPC) |
Type of Biomarker | Diagnostic |
Cohort | Cohort 1: mCRPC patients (n=25) Vs age matched controls (n = 25);Cohort 2: 21 mCRPC patients and 20 age-matched healthy controls collected at the University of Michigan. |
Senstivity | NA |
Specificity | NA |
AUC | Cohort 1: 0.678; Cohort 2: 0.652 |
Accuracy | NA |
Level Of Significance | p=0.022 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | miR-210 |