Biomarker ID | 1198 |
PMID | 23921786 |
Year | 2014 |
Biomarker | Angiogenin |
Biomarker Basis | Concentration based (pg/ml) |
Biomolecule | Protein |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in Patients with PCa (median): [Cancer 487,500 vs. Non Cancer: 414,800) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | NA |
Experiment | Prostate Cancer Vs Non Cancer |
Type of Biomarker | Diagnostic |
Cohort | 241 patients such that 151 did not have cancer and 90 did were included in the study |
Senstivity | 9000% |
Specificity | 1460% |
AUC | 0.59 (95% CI: 0.50–0.68) |
Accuracy | NA |
Level Of Significance | p = 0.008 |
Method Used | ELISA |
Clinical | No |
Remarks | Angiogenin < 230 000 was taken as cut off for calculating Sensitivity and Specificity. (Not for AUC) |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | ANG |