| Biomarker ID | 1184 |
| PMID | 23904377 |
| Year | 2013 |
| Biomarker | Bone Sialoprotein |
| Biomarker Basis | Concentration Based (Ï/ng-1ml-1) |
| Biomolecule | Protein |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Upregulated in Bone Metastatis (BM: 38.7 ±19.3; NBM: 9.1 ± 5.8) |
| Odds Ratio/Hazard Ratio/Relative Risk | BSP (<33.26, ≥33.26): [Multivariate Analyis: HR: 27.52 (95% CI: 1.121–29.27); p = 0.013] |
| Effect on Pathways | NA |
| Experiment | Bone Metastatis Vs No Bone Metastatis |
| Type of Biomarker | Prognostic |
| Cohort | 56 patients with Bone metastatis and 60 without Non Bone Metastatis were chosen for the study |
| Senstivity | 7821% |
| Specificity | 7928% |
| AUC | 0.854 |
| Accuracy | NA |
| Level Of Significance | p<0.05 |
| Method Used | Sandwich ELISA |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | BSP |