Biomarker ID | 1184 |
PMID | 23904377 |
Year | 2013 |
Biomarker | Bone Sialoprotein |
Biomarker Basis | Concentration Based (Ï/ng-1ml-1) |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in Bone Metastatis (BM: 38.7 ±19.3; NBM: 9.1 ± 5.8) |
Odds Ratio/Hazard Ratio/Relative Risk | BSP (<33.26, ≥33.26): [Multivariate Analyis: HR: 27.52 (95% CI: 1.121–29.27); p = 0.013] |
Effect on Pathways | NA |
Experiment | Bone Metastatis Vs No Bone Metastatis |
Type of Biomarker | Prognostic |
Cohort | 56 patients with Bone metastatis and 60 without Non Bone Metastatis were chosen for the study |
Senstivity | 7821% |
Specificity | 7928% |
AUC | 0.854 |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | Sandwich ELISA |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | BSP |