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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1178
PMID23896625
Year2013
BiomarkerSLCO2B1 rs12422149 (GG allele)
Biomarker BasisMutation Based
BiomoleculeMutation
SourceBlood
SubjectsHumans
RegulationNA
Odds Ratio/Hazard Ratio/Relative RiskHR: [0.589 (95% CI: 0.37–0.95)]
Effect on PathwaysPathways include: Transport of organic anions, Transport of vitamins, nucleosides, and related molecules, SLC-mediated transmembrane transport, Oncostatin M, Transmembrane transport of small molecules
ExperimentTime to Progression
Type of BiomarkerPrognostic
Cohort87 patients with Prostate Cancer were included in the study. Of the 87 patients, 76 progressed to CRPC and 53 died during the median follow-up duration of 39.5 months.
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep =0.028
Method UsedPCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NameNA