Biomarker Card
This biomarker card gives comprehensive information about each biomarker.
| Detailed Information | |
|---|---|
| Biomarker ID | 1177 |
| PMID | 23891454 |
| Year | 2013 |
| Biomarker | Genetic Risk score based on 41 SNPs (rs10187424, rs721048, rs1465618, rs13385191, rs12621278, rs2292884, rs4857841, rs6763931, rs10936632, rs17021918, rs12500426, rs7679673, rs2121875, rs12653946, rs130067, rs1983891, rs339331, rs9364554, rs10486567, rs6465657, rs1512268, rs1447295, rs6983561, rs16901979, rs10086908, rs12543663, rs620861, rs6983267, rs16902094, rs1016343, rs13252298, rs445114, rs10993994, rs4962416, rs10896449, rs11228565, rs12418451, rs10875943, rs9600079, rs4430796, rs11649743, rs1859962, rs8102476, rs17632542, rs2735839, rs9623117, rs5759167, rs5945619, rs5919432) |
| Biomarker Basis | Mutation Based |
| Biomolecule | Mutation |
| Source | Blood |
| Subjects | Humans |
| Regulation | Increased Score with Increased risk of Prostate Cancer |
| Odds Ratio/Hazard Ratio/Relative Risk | Univariate: [OR: 1.67 (95% CI: 1.11- 2.50); Multivariate: [OR: 1.60 (95% CI: 1.05-2.45)] |
| Effect on Pathways | NA |
| Experiment | Prostate Cancer Vs no Prostate Cancer |
| Type of Biomarker | Diagnostic |
| Cohort | 172 men from STHLM cohort underwent this study out of which 47 had prostate cancer |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | Univariate: p=0.014; Multivariate: 0.029 |
| Method Used | matrix- assisted laser desorption/ionization time-of-flight mass spectrometry |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |