Biomarker ID | 1173 |
PMID | 23846169 |
Year | 2013 |
Biomarker | miR-146b-3p |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Serum |
Subjects | Humans |
Regulation | Upregulated in patients with Biochemical Recurrence |
Odds Ratio/Hazard Ratio/Relative Risk | Univariate: [HR: 1.13 (95% CI: 1.01–1.26)]; Multivariate: [1.16 (95% CI: 1.03–1.31)] |
Effect on Pathways | Pathways Include:- synapse; neuron projection; cell projection; anatomical structure morphogenesis; nervous system development |
Experiment | Biochemical recurrence Vs No Biochemical Recurrence |
Type of Biomarker | Prognostic |
Cohort | 70 patients with Gleason 7 cancers treated by RP, 31 of whom had undergone disease progression following surgery were chosen for the study |
Senstivity | NA |
Specificity | NA |
AUC | 0.62 |
Accuracy | NA |
Level Of Significance | p = 0.02 |
Method Used | qRT–PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | miR-146b-3p |