Biomarker ID | 1166 |
PMID | 23840433 |
Year | 2013 |
Biomarker | Cyclin-dependent kinase 5, regulatory subunit 1 (CDK5R1) |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Downregulated in PCa |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: Lissencephaly gene (LIS1) in neuronal migration and development, Reelin signaling pathway, MAPK/TRK pathway, Ck1/Cdk5 regulation by type 1 glutamate receptors, CRMPs in Sema3A signaling |
Experiment | Cancerous Vs non cancerous conditions |
Type of Biomarker | Diagnostic |
Cohort | 50 cancerous and 44 non cancerous prostate specimens were included for the study |
Senstivity | NA |
Specificity | NA |
AUC | 0.719 (95% CI: 0.6.0-0.831) |
Accuracy | NA |
Level Of Significance | p<0.01 |
Method Used | RT - qPCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on human patient cohort |
Technical Name | NA |