| Biomarker ID | 1157 |
| PMID | 23826311 |
| Year | 2013 |
| Biomarker | Peptide ID: [7098; 8863; 9673; 10706; 24050] |
| Biomarker Basis | Concentration Based |
| Biomolecule | Protein |
| Source | Plasma |
| Subjects | Humans |
| Regulation | Downregulated in PCa [mean(control)/mean (case)]: [Peptide ID: [7098 (3.3 fold) ; 8863 (7.7 fold) ; 9673(73.1 fold) ; 10706 (124.8 fold) ; 24050( 11.1 fold)] |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | Prostate Cancer Vs Benign Prostatic Hyperplasia |
| Type of Biomarker | Diagnostic |
| Cohort | 125 samples were divided into a discovery set with 22 PCa, 14 Chronic Prostatis; 9 BPH and 5 Healthy Control samples and the remaining 48 PCa, 12 BPH, 11 CP, and 4HC samples into an independent test set |
| Senstivity | NA |
| Specificity | NA |
| AUC | Training: 0.99 (95% CI .90–0.99) |
| Accuracy | NA |
| Level Of Significance | p< 0.0027 |
| Method Used | capillary electrophoresis mass spectrometry |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | NA |