| Biomarker ID | 1149 |
| PMID | 23775525 |
| Year | 2013 |
| Biomarker | Insulin Like Growth Factor Binding Proteins (IGFBP-3) |
| Biomarker Basis | NA |
| Biomolecule | Protein |
| Source | Serum |
| Subjects | Humans |
| Regulation | Upregulated in Intervention Group |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include: Hypoxia and p53 in the cardiovascular system, Insulin-like growth factor (IGF) activity regulation by insulin-like growth factor binding proteins (IGFBPs), TAp63 pathway, Delta Np63 pathway, Ghrelin-mediated regulation of food intake and energy homeostasis |
| Experiment | Intervention Vs Control Group |
| Type of Biomarker | Predictive |
| Cohort | 19 overweight PCa patients were randomized to the intervention (N =10) or control (N = 9) group. The intervention group was subjected to 6-week, caloric-restricted diet and the control group was continued with their normal diet |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p = 0.002 |
| Method Used | ELISA |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | NA |