Biomarker ID | 1139 |
PMID | 23737455 |
Year | 2013 |
Biomarker | Aminoadipic acid |
Biomarker Basis | Concentration Based |
Biomolecule | Metabolites |
Source | Tissue |
Subjects | Humans |
Regulation | Increased in Patients with Recurrence |
Odds Ratio/Hazard Ratio/Relative Risk | HR: 2.51 (95% CI: 1.01–6.23) |
Effect on Pathways | NA |
Experiment | Recurrence Free Survival Vs No Recurrence Free Survival |
Type of Biomarker | Prognostic |
Cohort | Matched malignant and nonmalignant prostatectomy samples from 95 PCa patients were taken for the study. Data was available for 93 patients |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p =0.048 |
Method Used | gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS/MS) analysis |
Clinical | No |
Remarks | Univariate Analysis; Done between patients with Aminoadipic acid <1.85 and Aminoadipic acid ≥ 1.85 |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | NA |