| Biomarker ID | 113 |
| PMID | 19759844 |
| Year | 2008 |
| Biomarker | PCaP Polypeptide Panel (PCAPP) |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Urine |
| Subjects | Humans |
| Regulation | Differentially Expressed in Prostate Cancer |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | NA |
| Experiment | Prostate Cancer Vs Healthy Controls |
| Type of Biomarker | Diagnostic |
| Cohort | For Training set (n=86), patients with PCa (N = 51) and benign tissue (N = 35) were included in the study. For Testing set (n=264), patients with PCa (N = 118) and benign tissue (N = 95) were included in the study. |
| Senstivity | Training Set: 80% [95% CI: (67–90)] ; Testing Set: 73% [95% CI: (64–81)] |
| Specificity | Training Set: 97% [95% CI (85–99)]; Testing Set: 60% [95% CI (49–70)] |
| AUC | 0.7 |
| Accuracy | Test Set, using 213 Informative Samples:(57 TN, 32 FN, 86 TP, 38 FP) |
| Level Of Significance | p<0.05 |
| Method Used | CE-MS (Mass Spectrometry) |
| Clinical | No |
| Remarks | Polypeptide ID given as: (10054, 10442, 11645, 12064, 12202, 14707, 19070, 27863, 30451, 30566, 32748, 43009) |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on Independent Patient Dataset |
| Technical Name | NA |