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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1099
PMID23574937
Year2013
BiomarkermiR-205
Biomarker BasisExpression Based
BiomoleculemiRNA
SourcePlasma
SubjectsHumans
RegulationDownregulated with High Gleason Score
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways Include:DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; positive regulation of cellular metabolic process; positive regulation of metabolic process; nervous system development
ExperimentGleason Score < 7 Vs Gleason Score ≥ 8
Type of BiomarkerPrognostic
Cohort25 PCa patients with treatment-naive localized disease (localized PCa) and 25 patients with metastatic castration resistant PCa and a rising PSA (mCRPC patients) were chosen for the study
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep = 0.004
Method UsedNA
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityNot validated on independent patient dataset
Technical NamemiR-205