Biomarker ID | 1098 |
PMID | 23574937 |
Year | 2013 |
Biomarker | miR-423-3p |
Biomarker Basis | Expression Based |
Biomolecule | miRNA |
Source | Plasma |
Subjects | Humans |
Regulation | Upregulated with High Gleason Score |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways Include:- sequence-specific DNA binding; RNA binding; posttranscriptional regulation of gene expression; anatomical structure morphogenesis; sequence-specific double-stranded DNA binding |
Experiment | Gleason Score < 7 Vs Gleason Score ≥ 8 |
Type of Biomarker | Prognostic |
Cohort | 25 PCa patients with treatment-naive localized disease (localized PCa) and 25 patients with metastatic castration resistant PCa and a rising PSA (mCRPC patients) were chosen for the study |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p = 0.002 |
Method Used | NA |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | miR-423-3p |