Biomarker ID | 1089 |
PMID | 23554651 |
Year | 2010 |
Biomarker | Ribonuclease -L (RNASEL) [Arg462Gln Mutation] |
Biomarker Basis | Mutation Based |
Biomolecule | Mutation |
Source | NA |
Subjects | Humans |
Regulation | Increased Risk of PCA in African Population |
Odds Ratio/Hazard Ratio/Relative Risk | Gln/Gln vs Arg/Arg: [ OR = 2.50, (95% CI = 1.28-4.87)] ; Gln/Gln vs Gln/Arg + Arg/Arg: [OR = 2.54, 95% CI = 1.30-4.95] |
Effect on Pathways | Pathways include: Interferon alpha/beta signaling, Senescence and autophagy, Interferon signaling, Immune system signaling by interferons, interleukins, prolactin, and growth hormones, Immune system |
Experiment | Cases Vs Controls |
Type of Biomarker | Diagnostic |
Cohort | Meta- Analysis |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p<0.05 |
Method Used | NA |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | NA |
Technical Name | RNASEL |