| Biomarker ID | 1089 |
| PMID | 23554651 |
| Year | 2010 |
| Biomarker | Ribonuclease -L (RNASEL) [Arg462Gln Mutation] |
| Biomarker Basis | Mutation Based |
| Biomolecule | Mutation |
| Source | NA |
| Subjects | Humans |
| Regulation | Increased Risk of PCA in African Population |
| Odds Ratio/Hazard Ratio/Relative Risk | Gln/Gln vs Arg/Arg: [ OR = 2.50, (95% CI = 1.28-4.87)] ; Gln/Gln vs Gln/Arg + Arg/Arg: [OR = 2.54, 95% CI = 1.30-4.95] |
| Effect on Pathways | Pathways include: Interferon alpha/beta signaling, Senescence and autophagy, Interferon signaling, Immune system signaling by interferons, interleukins, prolactin, and growth hormones, Immune system |
| Experiment | Cases Vs Controls |
| Type of Biomarker | Diagnostic |
| Cohort | Meta- Analysis |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p<0.05 |
| Method Used | NA |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | NA |
| Technical Name | RNASEL |