| Biomarker ID | 1043 |
| PMID | 23342084 |
| Year | 2013 |
| Biomarker | Early Growth Response 3 (Egr3) |
| Biomarker Basis | Expression Based |
| Biomolecule | Protein |
| Source | Tissue |
| Subjects | Humans |
| Regulation | Upregulated in PCa (NSR (number of strong positive pixels ratio):normal prostate: 0.039 ; NSR: prostate cancer: 0.13) |
| Odds Ratio/Hazard Ratio/Relative Risk | NA |
| Effect on Pathways | Pathways include: Inhibition of activated T cell apoptosis by neuropeptides VIP and PACAP, Regulation of NFAT transcription factors, Differentiation pathway in PC12 cells, Interleukin-5 regulation of apoptosis, BDNF signaling pathway |
| Experiment | Prostate Cancer Vs Normal Prostate |
| Type of Biomarker | Diagnostic |
| Cohort | 20 prostate cancer samples from 11 patients and 3 normal prostate samples from 3 donors were chosen. (taken from The Human Protein Atlas (HPA): HPA006206) |
| Senstivity | NA |
| Specificity | NA |
| AUC | NA |
| Accuracy | NA |
| Level Of Significance | p = 0.00047 |
| Method Used | NA |
| Clinical | No |
| Remarks | NSR: (number of strong positive pixels ratio): strong positive pixels/total positive pixels |
| Clinical Trial Number | NA |
| Degree Of Validity | Validated on independent patient dataset |
| Technical Name | NA |