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Biomarker Card

This biomarker card gives comprehensive information about each biomarker.
Detailed Information
Biomarker ID1042
PMID23342084
Year2013
BiomarkerEarly Growth Response 3 (Egr3)
Biomarker BasisExpression Based
BiomoleculemRNA
SourceTissue
SubjectsHumans
RegulationUpregulated in PCa (5.35 fold)
Odds Ratio/Hazard Ratio/Relative RiskNA
Effect on PathwaysPathways include: Inhibition of activated T cell apoptosis by neuropeptides VIP and PACAP, Regulation of NFAT transcription factors, Differentiation pathway in PC12 cells, Interleukin-5 regulation of apoptosis, BDNF signaling pathway
ExperimentProstate Cancer Vs Normal Prostate
Type of BiomarkerDiagnostic
Cohort84 patients with Prostate cancer and 13 with normal prostate were selected for the study. (GEO GSE17951 and GEO GSE8218)
SenstivityNA
SpecificityNA
AUCNA
AccuracyNA
Level Of Significancep = 2 x 10^-15
Method UsedqRT-PCR
ClinicalNo
RemarksNA
Clinical Trial NumberNA
Degree Of ValidityValidated on independent patient dataset
Technical NameNA