Biomarker ID | 1042 |
PMID | 23342084 |
Year | 2013 |
Biomarker | Early Growth Response 3 (Egr3) |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in PCa (5.35 fold) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: Inhibition of activated T cell apoptosis by neuropeptides VIP and PACAP, Regulation of NFAT transcription factors, Differentiation pathway in PC12 cells, Interleukin-5 regulation of apoptosis, BDNF signaling pathway |
Experiment | Prostate Cancer Vs Normal Prostate |
Type of Biomarker | Diagnostic |
Cohort | 84 patients with Prostate cancer and 13 with normal prostate were selected for the study. (GEO GSE17951 and GEO GSE8218) |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p = 2 x 10^-15 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | NA |