Biomarker ID | 1036 |
PMID | 23308129 |
Year | 2013 |
Biomarker | BMI1 |
Biomarker Basis | Concentration Based (ng/mL) |
Biomolecule | Protein |
Source | Tissue |
Subjects | Humans |
Regulation | Upregulated in PCa: (Normal: 0.81 ± 0.07; PCa stage 2: 1.8 ± 0.08) |
Odds Ratio/Hazard Ratio/Relative Risk | NA |
Effect on Pathways | Pathways include: PRC2 complex long-term gene silencing through modification of histone tails, Myc active pathway, Senescence and autophagy, T cell receptor regulation of apoptosis |
Experiment | Normal Vs PCa |
Type of Biomarker | Diagnostic |
Cohort | 70 pair- matched specimens of normal and CaP representing all tumor stages were selected for the study |
Senstivity | NA |
Specificity | NA |
AUC | NA |
Accuracy | NA |
Level Of Significance | p< 0.05 |
Method Used | Immunohistochemistry; ELISA, western-blot |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Validated on independent patient dataset |
Technical Name | NA |