Biomarker ID | 1022 |
PMID | 23201468 |
Year | 2012 |
Biomarker | TMPRSS2-ERG (v-ets erythroblastosis virus E26 oncogene homolog) >= 10 |
Biomarker Basis | Expression Based |
Biomolecule | mRNA |
Source | Urine |
Subjects | Humans |
Regulation | NA |
Odds Ratio/Hazard Ratio/Relative Risk | OR: 7.16 (95% CI, 2.54-20.15) |
Effect on Pathways | NA |
Experiment | Gleason Score <7 Vs Gleason score ≥ 7 |
Type of Biomarker | Prognostic |
Cohort | 443 men were screened after biopsies, out of which 247 did not have prostate cancer and 196 had. |
Senstivity | NA |
Specificity | NA |
AUC | 0.840 (95% CI: 0.785–0.895) |
Accuracy | NA |
Level Of Significance | p<0.001 |
Method Used | qRT-PCR |
Clinical | No |
Remarks | NA |
Clinical Trial Number | NA |
Degree Of Validity | Not validated on independent patient dataset |
Technical Name | TMPRSS2-ERG |