| Biomarker ID | 1021 |
| PMID | 23201468 |
| Year | 2012 |
| Biomarker | TMPRSS2-ERG (v-ets erythroblastosis virus E26 oncogene homolog) >= 10 |
| Biomarker Basis | Expression Based |
| Biomolecule | mRNA |
| Source | Urine |
| Subjects | Humans |
| Regulation | TMPRSS2-ERG fusion upregulated in PCa (No PCa: 15; Pca: 46) |
| Odds Ratio/Hazard Ratio/Relative Risk | OR: 3.28 (95% CI: 1.57-6.85) |
| Effect on Pathways | NA |
| Experiment | PCa Vs No PCA group |
| Type of Biomarker | Diagnostic |
| Cohort | 443 men were screened after biopsies, out of which 247 did not have prostate cancer and 196 had. |
| Senstivity | NA |
| Specificity | 93.2% |
| AUC | 0.842 (95% CI: 0.806–0.878) |
| Accuracy | NA |
| Level Of Significance | p<0.001 |
| Method Used | qRT-PCR |
| Clinical | No |
| Remarks | NA |
| Clinical Trial Number | NA |
| Degree Of Validity | Not validated on independent patient dataset |
| Technical Name | TMPRSS2-ERG |