Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 2. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_323Canine parvovirusCPV2.NS1DNAParoviridaeCPV genome expressing non-structural protein (NS1)YesNoNoNCCS (National Centre for Cell Science, Pune, India)Human cervical cancer cell lineHeLadensity of E+4 to E+5 cells/well in 120 microlitres of culture mediumNALDH assayNA9% cancer cell death at 24 hoursNoNoNA No responseNAApoptosis is induced via mitochondrial depolarization, release of cytochrome-c and activation of caspase 9NANA26555166
OV_324Canine parvovirusCPV2.NS1DNAParoviridaeCPV genome expressing non-structural protein (NS1)YesNoNoNCCS (National Centre for Cell Science, Pune, India)Human cervical cancer cell lineHeLadensity of E+4 to E+5 cells/well in 120 microlitres of culture mediumNALDH assayNA18% cancer cell death at 48 hoursNoNoNA No responseNAApoptosis is induced via mitochondrial depolarization, release of cytochrome-c and activation of caspase 9NANA26555166