Browse By Oncolytic Virus Species Result Page of OvirusTdb
The Total number of records shown on this page is 10. Click on ID to see further detail.
IDOV_4646 | Virus nameBovine herpesvirus | Virus strainBHV-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5-AZa (0.5 micromolar/litre) | Immune gene insertion in viral genomeNo | Source of cell lineSt. Louis university | Origin of cell lineCotton rat tumor cell line | Cell lineLCRT | Concentration of cell line1.0E+5 cells per ml | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result87% cell viablity after 2 days, additive effect | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119103 |
IDOV_4647 | Virus nameBovine herpesvirus | Virus strainBHV-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5-AZa (0.5 micromolar/litre) | Immune gene insertion in viral genomeNo | Source of cell lineSt. Louis university | Origin of cell lineCotton rat tumor cell line | Cell lineLCRT | Concentration of cell line1.0E+5 cells per ml | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration3 MOI | In-vitro result80% cell viablity after 2 days, additive effect | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119103 |
IDOV_4648 | Virus nameBovine herpesvirus | Virus strainBHV-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5-AZa (0.5 micromolar/litre) | Immune gene insertion in viral genomeNo | Source of cell lineSt. Louis university | Origin of cell lineCotton rat tumor cell line | Cell lineLCRT | Concentration of cell line1.0E+5 cells per ml | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result56% cell viablity after 2 days, additive effect | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119103 |
IDOV_4649 | Virus nameBovine herpesvirus | Virus strainBHV-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5-AZa (1.0 micromolar/litre) | Immune gene insertion in viral genomeNo | Source of cell lineSt. Louis university | Origin of cell lineCotton rat tumor cell line | Cell lineLCRT | Concentration of cell line1.0E+5 cells per ml | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result74% cell viablity after 2 days, additive effect | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119103 |
IDOV_4650 | Virus nameBovine herpesvirus | Virus strainBHV-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5-AZa (1.0 micromolar/litre) | Immune gene insertion in viral genomeNo | Source of cell lineSt. Louis university | Origin of cell lineCotton rat tumor cell line | Cell lineLCRT | Concentration of cell line1.0E+5 cells per ml | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration3 MOI | In-vitro result79% cell viablity after 2 days, additive effect | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119103 |
IDOV_4651 | Virus nameBovine herpesvirus | Virus strainBHV-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5-AZa (1.0 micromolar/litre) | Immune gene insertion in viral genomeNo | Source of cell lineSt. Louis university | Origin of cell lineCotton rat tumor cell line | Cell lineLCRT | Concentration of cell line1.0E+5 cells per ml | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result56% cell viablity after 2 days, additive effect | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119103 |
IDOV_4652 | Virus nameBovine herpesvirus | Virus strainBHV-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5-AZa (3.0 micromolar/litre) | Immune gene insertion in viral genomeNo | Source of cell lineSt. Louis university | Origin of cell lineCotton rat tumor cell line | Cell lineLCRT | Concentration of cell line1.0E+5 cells per ml | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result59% cell viablity after 2 days, additive effect | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119103 |
IDOV_4653 | Virus nameBovine herpesvirus | Virus strainBHV-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5-AZa (3.0 micromolar/litre) | Immune gene insertion in viral genomeNo | Source of cell lineSt. Louis university | Origin of cell lineCotton rat tumor cell line | Cell lineLCRT | Concentration of cell line1.0E+5 cells per ml | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration3 MOI | In-vitro result60% cell viablity after 2 days, additive effect | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119103 |
IDOV_4654 | Virus nameBovine herpesvirus | Virus strainBHV-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5-AZa (3.0 micromolar/litre) | Immune gene insertion in viral genomeNo | Source of cell lineSt. Louis university | Origin of cell lineCotton rat tumor cell line | Cell lineLCRT | Concentration of cell line1.0E+5 cells per ml | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration5 MOI | In-vitro result60% cell viablity after 2 days, additive effect | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119103 |
IDOV_4655 | Virus nameBovine herpesvirus | Virus strainBHV-1 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationNone | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5-AZa (2mg/kg) intraperitoneal single dose | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismCR mice xenograft for LCRT cells (5.0E+5) | In-vivo virus concentration5.0E+6 pfu for 5 days | In-vivo toxicityNA | In-vivo resultCombination therapy results in 3/8 animals with delayed growth | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119103 |