Detailed description page of Selected OV_ID


OV_4655 details
Primary information
OV_IDOV_4655
Virus Name Bovine herpesvirus
StrainBHV-1
Virus typeDNA
Virus familyHerpesviridae
Modification in virus genomeNone
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with 5-AZa (2mg/kg) intraperitoneal single dose
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismCR mice xenograft for LCRT cells (5 × 10⁵)
In-vivo virus concentration5 × 10⁶ pfu for 5 days
In-vivo toxicityNA
In-vivo resultCombination therapy results in 3/8 animals with delayed growth
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectInduce antitumor immune response
Clinical trialNA
PMID27119103