Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 9. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5063Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCMurine lymphocytic leukemia cell lineL12101.0E+3 cells per wellNACrystal violet staining10 MOI96% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762
OV_5064Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCMurine ovarian cell lineID81.0E+3 cells per wellNACrystal violet staining10 MOI100% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762
OV_5065Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCHuman pancreatic cancer cell linePC-31.0E+3 cells per wellNACrystal violet staining10 MOI80% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762
OV_5066Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCHuman cervical cancer cell lineHeLa1.0E+3 cells per wellNACrystal violet staining10 MOI50% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762
OV_5067Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCMycobacterium tubeculosis cell line22RV11.0E+3 cells per wellNACrystal violet staining10 MOI40% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762
OV_5068Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCHuman prostate cancer cell lineDu1451.0E+3 cells per wellNACrystal violet staining10 MOI70% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762
OV_5069Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCHuman colorectal cancer cell lineHCT-1161.0E+3 cells per wellNACrystal violet staining10 MOI100% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762
OV_5070Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCHuman lung carcinoma cell lineA5491.0E+3 cells per wellNACrystal violet staining10 MOI80% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762
OV_5071Avian orthoreovirusARV-PB1RNAReoviridaeNoneYesNoNoATCCHuman epithelial ovarian carcinomaSKOV31.0E+3 cells per wellNACrystal violet staining10 MOI70% cell viability after 96 hoursNoNoNA No responseNAInduction of apoptosisInduction of Interferon related gene expressionNA28441762