The Total number of records shown on this page is 51. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_5844	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human colon carcinoma cell line	SW620	80% confluency	NA	NA	55 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5845	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human colon carcinoma cell line	HT-29	80% confluency	NA	NA	1 ×10⁶ pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5846	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human head and neck carcinoma cell line	KB	80% confluency	NA	NA	4 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5847	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human head and neck carcinoma cell line	A253	80% confluency	NA	NA	2.7 ×10³ pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5848	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human head and neck carcinoma cell line	FaDu	80% confluency	NA	NA	2.9 ×10³ pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5849	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human head and neck carcinoma cell line	Hep-2	80% confluency	NA	NA	1.5 ×10⁴ pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5850	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human neuroepithelia cancer cell line	SK-N-MC	80% confluency	NA	NA	20 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5851	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human small cell lung carcinoma cell line	DMS-114	80% confluency	NA	NA	48 pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5852	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human small cell lung carcinoma cell line	DMS-153	80% confluency	NA	NA	1.1 ×10⁵ pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5853	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human small cell lung carcinoma cell line	NCI-H345	80% confluency	NA	NA	1.2 ×10⁶ pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5854	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human small cell prostae carcinoma cell line	NCI-H660	80% confluency	NA	NA	1.0 ×10⁵ pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5855	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	Human leukemia cell line	K562	80% confluency	NA	NA	5.4 ×10⁴ pfu	50% cancer cell death	No	No	NA	No response	NA	NA	NA	NA	US8105578
OV_5856	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for HT1080 (10 million)	3.0E+8 pfu	NA	Complete regression in tumor in 11 mouse out of 12	Intratumoral	NA	NA	NA	US8105578
OV_5857	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for PA-1 (10 million)	3.0E+8 pfu	NA	Complete regression in tumor in 9 mouse out of 9	Intratumoral	NA	NA	NA	US8105578
OV_5858	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for KB (10 million)	3.0E+8 pfu	NA	Complete regression in tumor in 7 mouse out of 12	Intratumoral	NA	NA	NA	US8105578
OV_5859	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for SKMEL5 (10 million)	3.0E+8 pfu	NA	Complete regression in tumor in 5 mouse out of 8	Intratumoral	NA	NA	NA	US8105578
OV_5860	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+8 pfu	NA	Complete regression in tumor in 1 mouse out of 8	Intratumoral	NA	NA	NA	US8105578
OV_5861	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for U87MG (10 million)	3.0E+8 pfu	NA	Complete regression in tumor in 1 mouse out of 9	Intratumoral	NA	NA	NA	US8105578
OV_5862	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	1.5E+9 pfu	NA	Complete regression in 2 out of 8 (tumor dimension 8 - 9.5 mm)	Intratumoral	NA	NA	NA	US8105578
OV_5863	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	9.0E+8 pfu	NA	Complete regression in 7 out of 8 (tumor dimension 8 - 9.5 mm)	Intratumoral	NA	NA	NA	US8105578
OV_5864	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+8 pfu	NA	Complete regression in 3 out of 8 (tumor dimension 8 - 9.5 mm)	Intratumoral	NA	NA	NA	US8105578
OV_5865	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+8 pfu	NA	Complete regression in 3 out of 3 (tumor dimension 10 - 11 mm)	Intratumoral	NA	NA	NA	US8105578
OV_5866	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+8 pfu	NA	Complete regression in 3 out of 3 (tumor dimension 10 - 11 mm)	Intratumoral	NA	NA	NA	US8105578
OV_5867	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+8 pfu	NA	Complete regression in 3 out of 3 (tumor dimension 10 - 11 mm)	Intratumoral	NA	NA	NA	US8105578
OV_5868	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	1.5E+9 pfu	NA	Complete regression in tumor volume in 2 out of total 6 (tumor volume <300mm)	Intratumoral	NA	NA	NA	US8105578
OV_5869	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	9.0E+8 pfu	NA	Complete regression in tumor volume in 3 out of total 4 (tumor volume <300mm)	Intratumoral	NA	NA	NA	US8105578
OV_5870	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+8 pfu	NA	Complete regression in tumor volume in 2 out of total 6 (tumor volume <300mm)	Intratumoral	NA	NA	NA	US8105578
OV_5871	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	1.5E+9 pfu	NA	Complete regression in tumor volume in 3 out of total 5 (tumor volume >300mm)	Intratumoral	NA	NA	NA	US8105578
OV_5872	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	9.0E+8 pfu	NA	Complete regression in tumor volume in 7 out of total 7 (tumor volume >300mm)	Intratumoral	NA	NA	NA	US8105578
OV_5873	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+10 pfu	NA	Complete regression in tumor volume in 4 out of total 5 (tumor volume >300mm)	Intratumoral	NA	NA	NA	US8105578
OV_5874	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	1.5E+9 pfu	NA	Complete reduction in tumor 7 out of 7 (tumor dimension 10 - 11.5 mm)	Intratumoral	NA	NA	NA	US8105578
OV_5875	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+8 pfu	NA	Complete reduction in tumor 6 out of 7 (tumor dimension 10 - 11.5 mm)	Intratumoral	NA	NA	NA	US8105578
OV_5876	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+7 pfu	NA	Complete reduction in tumor 5 out of 7 (tumor dimension 10 - 11.5 mm)	Intratumoral	NA	NA	NA	US8105578
OV_5877	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+6 pfu	NA	Complete reduction in tumor 5 out of 7 (tumor dimension 10 - 11.5 mm)	Intratumoral	NA	NA	NA	US8105578
OV_5878	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	1.5E+9 pfu	NA	Complete reduction in tumor volume 7 out of 7 (Tumor volume >300mm)	Intratumoral	NA	NA	NA	US8105578
OV_5879	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+8 pfu	NA	Complete reduction in tumor volume 6 out of 7 (Tumor volume >300mm)	Intratumoral	NA	NA	NA	US8105578
OV_5880	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+7 pfu	NA	Complete reduction in tumor volume 4 out of 6 (Tumor volume >300mm)	Intratumoral	NA	NA	NA	US8105578
OV_5881	Newcastle disease virus	NDV-PPMK107	RNA	Paramyxoviridae	None	Yes	No	Yes	NA	NA	NA	NA	NA	NA	NA	NA	Athymic mice xenograft for A375 (10 million)	3.0E+6 pfu	NA	Complete reduction in tumor volume 4 out of 6 (Tumor volume >300mm)	Intratumoral	NA	NA	NA	US8105578
OV_5902	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	5E+5 pfu	NA	LDH release assay	0.1 MOI	50% of cancer cell death occurs after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5903	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	5E+5 pfu	NA	LDH release assay	0.1 MOI	No cell death observed after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5904	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human pancreatic cancer cell line	PANC-1	5E+5 pfu	NA	LDH release assay	0.1 MOI	100% cell killing observed after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5905	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human pancreatic cancer cell line	MIA paCa-2	5E+5 pfu	NA	LDH release assay	0.1 MOI	30% cell killing observed after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5906	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human neck and head carcinoma cell line	SCC	5E+5 pfu	NA	LDH release assay	0.1 MOI	60% cell killing after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5907	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human neck and head carcinoma cell line	SCC	5E+5 pfu	NA	LDH release assay	0.1 MOI	No cell death observed after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5908	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human neck and head carcinoma cell line	SCC	5E+5 pfu	NA	LDH release assay	0.1 MOI	100% cell killing observed after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5909	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human neck and head carcinoma cell line	SCC	5E+5 pfu	NA	LDH release assay	0.1 MOI	70% cell killing after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5910	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human melanoma cell line	SK MEL-2	5E+5 pfu	NA	LDH release assay	0.1 MOI	100% cell killing observed after 3 days	No	No	NA		NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5911	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human melanoma cell line	B16-F10	5E+5 pfu	NA	LDH release assay	0.1 MOI	40% cell killing after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5912	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human melanoma cell line	SK MEL-2	5E+5 pfu	NA	LDH release assay	0.1 MOI	100% cell killing observed after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5913	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human melanoma cell line	B16-F10	5E+5 pfu	NA	LDH release assay	0.1 MOI	30% cell killing after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5914	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice xenograft for B16-F10 (1.0E+5)	5.0E+6 pfu	NA	Complete regression in tumor volume after 25 days	Intratumoral	NA	Virus induced IFN-gamma production	NA	US10035984