Browse By Model Organism Result Page of OvirusTdb

The total number of records retrieved from this search are 1. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_46AdenovirusAd-cycEDNAAdenoviridaeE1b-deleted mutant with a human cyclin E promoter driving an intact E1A expression cassetteYesNoNoNANANANANANANANAFemale FVB/NCr mice isograft for 5.0E+6 cells ED-1 murine lung cancer cell lines1.5E+9 IFU (on 0, 2, 4 and 6 days)NA Reduction in tumor volume to 52 cubic millimeter compared to control 150 cubic millimeter after 36 daysIntratumorallyNAActivates CDK2 and targets the transcriptional repressor pRbNA26475304