Browse By Model Organism Result Page of OvirusTdb

The total number of records retrieved from this search are 1. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_4979Vaccinia virusvv-IL-24DNAPoxviridaeInsertion of IL-24 gene in tk locusYesNoVirus expressing IL-24 geneNANANANANANANANAC54BL/6 mice xenograft for A549 cell line (5.0E+6)1.0E+7 pfuNA Reduction in tumor volume to 1000 cubic mm compared to control 2200 cubic mm after 27 daysIntratumoralInduction of apoptosisNANA27208781