Browse By Model Organism Result Page of OvirusTdb

The total number of records retrieved from this search are 3. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5674Herpes simplex virusHSV-G47-deltaDNAHerpesviridaeDeletion mutatnt for Gamma 34.5, ICP6 and ICP47 geneYesNoNoNANANANANANANANAA/J mice isograft for Neuro2a cell line (5.0E+6)1.0E+6 pfuNA Reduction in tumor volume to 2500mm after 17 daysIntratumoralNAInduction of IL-12 and IFn-gamma productionNAUS7655459
OV_5675Herpes simplex virusHSV-G47-deltaDNAHerpesviridaeDeletion mutatnt for Gamma 34.5, ICP6 and ICP47 geneNoVirus in combination with IL-18NoNANANANANANANANAA/J mice isograft for Neuro2a cell line (5.0E+6)1.0E+6 pfuNA Reduction in tumor volume below 500mm after 17 daysIntratumoralNAInduction of IL-12 and IFn-gamma productionNAUS7655459
OV_5676Herpes simplex virusHSV-G47-deltaDNAHerpesviridaeDeletion mutatnt for Gamma 34.5, ICP6 and ICP47 geneNoVirus in combination with IL-18 (1microgram/day)NoNANANANANANANANAA/J mice isograft for Neuro2a cell line (5.0E+6)2.0E+6 pfuNA Reduction in tumor volume to 700mm after 15 days compared to control 2200mmIntratumoralNAInduction of IL-12 and IFn-gamma productionNAUS7655459