Browse By Model Organism Result Page of OvirusTdb
The total number of records retrieved from this search are 1. Click on ID to see further detail.
IDOV_5338 | Virus nameNewcastle disease virus | Virus strainNDV/Anh-TRAIL | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationVirus insertion for TRAIL gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismKumming mice implanted for 5.0E+5 H22 cells | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultReduction in tumor volume to 10 cubic mm compared to control 3500 cubic mm after 14 days | Mode of deliveryIntratumoral | Pathway inducedVirus induced apoptosis as measured by TUNEL assay | Immunogenic effectCaspase 3 pathway are activated | Clinical trialNA | PMID28246027 |