Browse By Model Organism Result Page of OvirusTdb

The total number of records retrieved from this search are 1. Click on ID to see further detail.
IDOV_5338Virus nameNewcastle disease virusVirus strainNDV/Anh-TRAILVirus genome typeRNAVirus familyParamyxoviridaeVirus genome modificationVirus insertion for TRAIL geneVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismKumming mice implanted for 5.0E+5 H22 cellsIn-vivo virus concentration1.0E+7 pfuIn-vivo toxicityNA In-vivo resultReduction in tumor volume to 10 cubic mm compared to control 3500 cubic mm after 14 daysMode of deliveryIntratumoralPathway inducedVirus induced apoptosis as measured by TUNEL assayImmunogenic effectCaspase 3 pathway are activatedClinical trialNAPMID28246027