Browse By Model Organism Result Page of OvirusTdb

The total number of records retrieved from this search are 2. Click on ID to see further detail.
IDOV_5894Virus nameAdenovirusVirus strainCGTG-602Virus genome typeDNAVirus familyAdenoviridaeVirus genome modificationVirus E1A promoter is replaced by human E2F1 promoterVirus aloneYesVirus in combination with drug/radiationNoImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHamster xenograft for HAPT-1 (7.0E+6)In-vivo virus concentration3.0E+8 pfuIn-vivo toxicityNA In-vivo resultTumor volume reduced to 300mm after 18 days compared to control 800mmMode of deliveryIntratumoralPathway inducedNAImmunogenic effectNAClinical trialNAPMIDUS9410129
IDOV_5895Virus nameAdenovirusVirus strainCGTG-602Virus genome typeDNAVirus familyAdenoviridaeVirus genome modificationVirus E1A promoter is replaced by human E2F1 promoterVirus aloneNoVirus in combination with drug/radiationVirus in combination with cyclosporinImmune gene insertion in viral genomeNoSource of cell lineNAOrigin of cell lineNACell lineNAConcentration of cell lineNAIn-vitro toxicityNAAssayNAIn-vitro virus concentrationNAIn-vitro resultNAModel organismHamster xenograft for HAPT-1 (7.0E+6)In-vivo virus concentration3.0E+8 pfuIn-vivo toxicityNA In-vivo resultTumor volume reduced to 300mm after 18 days compared to control 800mmMode of deliveryIntratumoralPathway inducedNAImmunogenic effectNAClinical trialNAPMIDUS9410129