Detailed description page of Selected OV_ID


OV_5895 details
Primary information
OV_IDOV_5895
Virus Name Adenovirus
StrainCGTG-602
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeVirus E1A promoter is replaced by human E2F1 promoter
Virus aloneNo
Virus in combination iwth drug/radiationVirus in combination with cyclosporin
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismHamster xenograft for HAPT-1 (7 ×10⁶)
In-vivo virus concentration3 ×10⁸ pfu
In-vivo toxicityNA
In-vivo resultTumor volume reduced to 300mm after 18 days compared to control 800mm
Mode of deliveryIntratumoral
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMIDUS9410129