Browse By Model Organism Result Page of OvirusTdb

The total number of records retrieved from this search are 6. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_5544Herpes simplex virusMutantDNAHerpesviridaeDeletion mutatnt in TK gene and UL 24 geneYesNoNoATCCHuman malignant cell lineU87NANANANANAFisher male mice xenograft subcutaneous for U86 (3.0E+6)5.0E+6 pfuNA Tumor size was significantly smaller in treated mice compared to controlIntravenouslyNANANAUS6770274
OV_5545Herpes simplex virusMutantDNAHerpesviridaeDeletion mutatnt in TK gene and UL 24 geneYesNoNoATCCHuman malignant cell lineU87NANANANANAFisher male mice xenograft subrenal for U86 (3.0E+6)5.0E+6 pfuNA Tumor size was significantly smaller in treated mice compared to controlIntravenouslyNANANAUS6770274
OV_5546Herpes simplex virusMutantDNAHerpesviridaeDeletion mutatnt in TK gene and UL 24 geneYesNoNoATCCHuman malignant cell lineU87NANANANANAFisher male mice xenograft intracerebral for U86 (1.6E+5)1.0E+3 pfuNA Three of seven mice survived after 7 weekIntravenouslyNANANAUS6770274
OV_5547Herpes simplex virusMutantDNAHerpesviridaeDeletion mutatnt in TK gene and UL 24 geneYesNoNoATCCHuman malignant cell lineU87NANANANANAFisher male mice xenograft intracerebral for U86 (1.6E+5)1.0E+5 pfuNA Four of seven mice survived after 7 weekIntravenouslyNANANAUS6770274
OV_5548Herpes simplex virusMutantDNAHerpesviridaeDeletion mutatnt in TK gene and UL 24 geneYesNoNoATCCHuman malignant cell lineU87NANANANANAFisher male mice xenograft intracerebral for U86 (1.6E+5)1.0E+3 pfuNA All mice was dead after week 14IntravenouslyNANANAUS6770274
OV_5549Herpes simplex virusMutantDNAHerpesviridaeDeletion mutatnt in TK gene and UL 24 geneYesNoNoATCCHuman malignant cell lineU87NANANANANAFisher male mice xenograft intracerebral for U86 (1.6E+5)1.0E+5 pfuNA Two of seven mice survived after 14 weekIntravenouslyNANANAUS6770274