The total number of records retrieved from this search are 6. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
IDOV_5544	Virus nameHerpes simplex virus	Virus strainMutant	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationDeletion mutatnt in TK gene and UL 24 gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman malignant cell line	Cell lineU87	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismFisher male mice xenograft subcutaneous for U86 (3.0E+6)	In-vivo virus concentration5.0E+6 pfu	In-vivo toxicityNA	In-vivo resultTumor size was significantly smaller in treated mice compared to control	Mode of deliveryIntravenously	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMIDUS6770274
IDOV_5545	Virus nameHerpes simplex virus	Virus strainMutant	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationDeletion mutatnt in TK gene and UL 24 gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman malignant cell line	Cell lineU87	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismFisher male mice xenograft subrenal for U86 (3.0E+6)	In-vivo virus concentration5.0E+6 pfu	In-vivo toxicityNA	In-vivo resultTumor size was significantly smaller in treated mice compared to control	Mode of deliveryIntravenously	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMIDUS6770274
IDOV_5546	Virus nameHerpes simplex virus	Virus strainMutant	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationDeletion mutatnt in TK gene and UL 24 gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman malignant cell line	Cell lineU87	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismFisher male mice xenograft intracerebral for U86 (1.6E+5)	In-vivo virus concentration1.0E+3 pfu	In-vivo toxicityNA	In-vivo resultThree of seven mice survived after 7 week	Mode of deliveryIntravenously	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMIDUS6770274
IDOV_5547	Virus nameHerpes simplex virus	Virus strainMutant	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationDeletion mutatnt in TK gene and UL 24 gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman malignant cell line	Cell lineU87	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismFisher male mice xenograft intracerebral for U86 (1.6E+5)	In-vivo virus concentration1.0E+5 pfu	In-vivo toxicityNA	In-vivo resultFour of seven mice survived after 7 week	Mode of deliveryIntravenously	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMIDUS6770274
IDOV_5548	Virus nameHerpes simplex virus	Virus strainMutant	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationDeletion mutatnt in TK gene and UL 24 gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman malignant cell line	Cell lineU87	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismFisher male mice xenograft intracerebral for U86 (1.6E+5)	In-vivo virus concentration1.0E+3 pfu	In-vivo toxicityNA	In-vivo resultAll mice was dead after week 14	Mode of deliveryIntravenously	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMIDUS6770274
IDOV_5549	Virus nameHerpes simplex virus	Virus strainMutant	Virus genome typeDNA	Virus familyHerpesviridae	Virus genome modificationDeletion mutatnt in TK gene and UL 24 gene	Virus aloneYes	Virus in combination with drug/radiationNo	Immune gene insertion in viral genomeNo	Source of cell lineATCC	Origin of cell lineHuman malignant cell line	Cell lineU87	Concentration of cell lineNA	In-vitro toxicityNA	AssayNA	In-vitro virus concentrationNA	In-vitro resultNA	Model organismFisher male mice xenograft intracerebral for U86 (1.6E+5)	In-vivo virus concentration1.0E+5 pfu	In-vivo toxicityNA	In-vivo resultTwo of seven mice survived after 14 week	Mode of deliveryIntravenously	Pathway inducedNA	Immunogenic effectNA	Clinical trialNA	PMIDUS6770274